At least five people have reportedly been killed in a blast that occurred near an under-construction building on the Mall Road in Chaman on Monday, according to the police.
Around 10 others have reportedly been injured in the blast.
Security forces have cordoned off the area whereas the injured have been taken to a nearby hospital.
At least one person was killed and six others were injured after an explosion in Turbat bazaar on July 21.
The city, approximately 700 kilometres from the provincial capital of Quetta, has been frequently targeted by militants.
According to law enforcement agencies, an improvised explosive device (IED) was fitted on a motorcycle. As a result of the explosion, a nearby mechanic shop was completely destroyed by fire.
Following the incident, the provincial chief minister, Jam Kamal Khan, expressed grief at the loss of life and said anti-state elements will not succeed in their nefarious plans.
The chief minister added that certain elements want to derail Balochistan from the path of progress and prosperity, but the people and government will continue on the path and such elements will be defeated.
The province, in recent months, has seen an increase in attacks.